From: Outcome-volume relationships and transhiatal esophagectomy: minimizing failure to rescue
Variable | All cases | Group 1 | Group 2 | Group 3 | Group 4 | P-value |
---|---|---|---|---|---|---|
Male: Female | 5:1 | 6:1 | 5:1 | 4:1 | 9:1 | 0.41 |
Median age at operation, years (range) | 62 (40-82) | 62 (46-82) | 62 (40-77) | 62 (40-80) | 64 (46-80) | 0.54 |
Smoking history (%) | 74 | 82 | 78 | 72 | 62 | 0.12 |
Body Mass Index (kg/m2) | 27.6 | 27.9 | 26.9 | 28.4 | 27.3 | 0.63 |
Mean pre-operative albumin (g/dL) | 3.7 | 3.5 | 3.7 | 3.7 | 3.7 | 0.054 |
1 or more comorbidities (%)† | 62 | 60 | 60 | 56 | 70 | 0.52 |
Histology (%)‡ | 0.06 | |||||
Adenocarcinoma | 60 | 82 | 80 | 74 | 74 | |
Squamous cell carcinoma | 16 | 10 | 10 | 14 | 13 | |
High grade dysplasia / CIS | 18 | 6 | 4 | 8 | 9 | |
Other | 2 | 2 | 2 | 0 | 2 | |
Pre-Operative Stage (%)§ | 0.40 | |||||
0 | 0 | 2 | 0 | 0 | 0 | |
I | 18 | 2 | 26 | 20 | 24 | |
II | 11 | 4 | 6 | 12 | 22 | |
III | 27 | 10 | 34 | 34 | 28 | |
IV | 3 | 0 | 2 | 4 | 6 | |
Unknown | 41 | 82 | 32 | 30 | 20 | |
Post-Operative Stage (%) | 0.51 | |||||
0 | 26 | 20 | 22 | 22 | 23 | |
I | 22 | 40 | 16 | 26 | 26 | |
II | 24 | 18 | 32 | 22 | 24 | |
III | 28 | 20 | 22 | 22 | 23 | |
IV | 0 | 0 | 2 | 0 | 1 | |
Neoadjuvant therapy (%) | 60 | 40 | 56 | 68 | 74 | 0.003* |