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Table 1 Patient demographics, baseline pulmonary, and GER evaluation

From: A preliminary investigation of anti-reflux intervention for gastroesophageal reflux related childhood-to-adult persistent asthma

Variables Total (n = 57)
Sex, M/F 18/39
Age (range), years 47.3 ± 13.3 (20–81)
Smoker/nonsmoker 4/53
Wheezing onset age (range), years 10.2 ± 4.5 (1–16)
Duration of wheezing (range), years 38.1 ± 12.7 (10–70)
Lung function test  
 FVC, L (% predicted) 3.1 ± 0.9 (93.2 ± 20.6%)
 FEV1, L (% predicted) 1.67 ± 0.7 (62.8 ± 21.8%)
 FEF, L/sec (% predicted) 4.5 ± 2.2 (66.9 ± 26.3%)
 FEV1/FVC 54.6 ± 14.9%
 FEV1/FVC < 70%, 30%–49%, < 30% 17 (29.8%), 13 (22.8%), 1 (1.8%)
Blood eosinophil count, cells/mm 3 (P%) 305.2 ± 325.3 (17.5%)
Esophageal endoscopy  
 Esophagitis (P%) 27 (47.4%)
 LA-A, LA-B, LA-C, LA-D 14, 10, 2, 1
 Barrett esophagus (P%) 1 (1.8%)
 Hiatal hernia (P%) 20 (35.1%)
Dual 24 hour pH monitoring  
 Distal channel DMS (P%) 41.94 ± 59.11 (64.9%)
 Proximal channel DMS (rang) 8.12 ± 10.23 (0.20 - 50.77)
High-resolution manometry  
 MUESP, mmHg (P%) 41.2 ± 22.7 (50.9%)
 MLESP, mmHg (P%) 14.2 ± 6.9 (43.9%)
 LHPZ, cm (P%) 2.9 ± 0.7 (35.1%)
 Esophageal dyskinesia 26 (45.6%)
  1. LA, Los Angeles classification; DMS, DeMeester score; MUESP, mean upper esophageal sphincter pressure (Normal range: 34–104 mmHg); MLESP, mean lower esophageal sphincter pressure (Normal range: 13–43 mmHg); LHPZ, length of high pressure zone (Normal range: 2.7–4.8 cm); P%: percentage of positive finding.