Table 1 Patient demographics, baseline pulmonary, and GER evaluation
Variables | Total (n = 57) |
|---|---|
Sex, M/F | 18/39 |
Age (range), years | 47.3 ± 13.3 (20–81) |
Smoker/nonsmoker | 4/53 |
Wheezing onset age (range), years | 10.2 ± 4.5 (1–16) |
Duration of wheezing (range), years | 38.1 ± 12.7 (10–70) |
Lung function test | |
FVC, L (% predicted) | 3.1 ± 0.9 (93.2 ± 20.6%) |
FEV1, L (% predicted) | 1.67 ± 0.7 (62.8 ± 21.8%) |
FEF, L/sec (% predicted) | 4.5 ± 2.2 (66.9 ± 26.3%) |
FEV1/FVC | 54.6 ± 14.9% |
FEV1/FVC < 70%, 30%–49%, < 30% | 17 (29.8%), 13 (22.8%), 1 (1.8%) |
Blood eosinophil count, cells/mm 3 (P%) | 305.2 ± 325.3 (17.5%) |
Esophageal endoscopy | |
Esophagitis (P%) | 27 (47.4%) |
LA-A, LA-B, LA-C, LA-D | 14, 10, 2, 1 |
Barrett esophagus (P%) | 1 (1.8%) |
Hiatal hernia (P%) | 20 (35.1%) |
Dual 24 hour pH monitoring | |
Distal channel DMS (P%) | 41.94 ± 59.11 (64.9%) |
Proximal channel DMS (rang) | 8.12 ± 10.23 (0.20 - 50.77) |
High-resolution manometry | |
MUESP, mmHg (P%) | 41.2 ± 22.7 (50.9%) |
MLESP, mmHg (P%) | 14.2 ± 6.9 (43.9%) |
LHPZ, cm (P%) | 2.9 ± 0.7 (35.1%) |
Esophageal dyskinesia | 26 (45.6%) |