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Table 1 Pattern of Antibiotic Prophylaxis

From: Odontostomatologic management of patients receiving oral anticoagulant therapy: a retrospective multicentric study

DRUGS

DOSAGE

FIRST CHOICE

Amoxicillin

Adults: 2 gm per os, 1 hour before surgery

1,5 gm per os, 6 hours after initial dose

Children: 50 mg/Kg per os, 1 hour before surgery

PATIENTS UNABLE TO TAKE DRUGS PER OS

Ampicillin

Adults: 2 gm i.m., before surgery

Children: 50 mg/Kg ev or im, 30 min before surgery

IN CASE OF ALLERGY TO PENICILLIN

Clindamycin

Cephalexin* or Cephadroxil*

Azithromycin or Clarithromycin

Adults: 600 mg per os, 1 hour before surgery

Children: 20 mg/Kg per os, 1 hour before surgery

Adults: 2 gr per os, 1 hour before surgery

Children: 50 mg/Kg per os, 1 hour before surgery

Adults: 500 mg × os 1 hour before surgery

Children: 15 mg/Kg per os, 1 hour before surgery

ALLERGIC PATIENTS UNABLE TO TAKE DRUGS PER OS

Clindamycin

Cephazolin*

Adults: 600 mg ev, 30 min before surgery

Children: 20 mg/Kg ev, 30 min before surgery

Adults: 1 gr im, 30 min before surgery

Children: 25 mg/Kg im or ev, 30 min before surgery

  1. *provided that there are no serious allergic reactions to penicillin