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Table 1 Pattern of Antibiotic Prophylaxis

From: Odontostomatologic management of patients receiving oral anticoagulant therapy: a retrospective multicentric study

DRUGS DOSAGE
FIRST CHOICE
Amoxicillin Adults: 2 gm per os, 1 hour before surgery
1,5 gm per os, 6 hours after initial dose
Children: 50 mg/Kg per os, 1 hour before surgery
PATIENTS UNABLE TO TAKE DRUGS PER OS
Ampicillin Adults: 2 gm i.m., before surgery
Children: 50 mg/Kg ev or im, 30 min before surgery
IN CASE OF ALLERGY TO PENICILLIN
Clindamycin
Cephalexin* or Cephadroxil*
Azithromycin or Clarithromycin
Adults: 600 mg per os, 1 hour before surgery
Children: 20 mg/Kg per os, 1 hour before surgery
Adults: 2 gr per os, 1 hour before surgery
Children: 50 mg/Kg per os, 1 hour before surgery
Adults: 500 mg × os 1 hour before surgery
Children: 15 mg/Kg per os, 1 hour before surgery
ALLERGIC PATIENTS UNABLE TO TAKE DRUGS PER OS
Clindamycin
Cephazolin*
Adults: 600 mg ev, 30 min before surgery
Children: 20 mg/Kg ev, 30 min before surgery
Adults: 1 gr im, 30 min before surgery
Children: 25 mg/Kg im or ev, 30 min before surgery
  1. *provided that there are no serious allergic reactions to penicillin