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Figure 4 | Annals of Surgical Innovation and Research

Figure 4

From: Topical recombinant thrombin at a concentration of 1000 IU/mL reliably shortens in vivo TTH and delivers durable hemostasis in the presence of heparin anticoagulation and clopidogrel platelet inhibition in a rabbit model of vascular bleeding

Figure 4

Effect of rThrombin concentration on rabbit blood thromboelastograph (TEG) parameters. Blood samples were collected from study animals (N = 3) two hours after they had been treated with clopidogrel, and heparin was added to 1 U/mL. The top panel shows the alpha angle, which is a function of the rate of clot formation, and the bottom panel shows the maximum clot strength (Gmax); alpha and Gmax are shown over a titrated range of rThrombin activity that was added to the TEG reaction.

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Annals of Surgical Innovation and Research

ISSN: 1750-1164

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